SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c9e386da25364a30780628c5ac9f2d93f5c5ed1d1e5324397aec4789e0c4cc' 
  AND token = 'XsBxKEDyRKCEU3GUm7ZQlNdsPn7K/VluJiGIuTtCKAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}