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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3bd701bc01a93b5893f4d9f19f09549fea693f245ff7a4c80c612d86c028808' 
  AND token = '0sES/N69nmw5Wu3qXFwpjISt29qn1d09wQY4BLTUXcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}