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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e27042fff689ba2cea7490245dc01bb42058bd27f50d3f2b6ba5fcbe545c004' 
  AND token = 'Ew+LNO7N2AxZYls3fkcVxyPStdtC+ss3nv1qqaX5Fxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}