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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b225ce7bdba023163c1948a01030e16fea50419ae74b23177b33b3f15812c093' 
  AND token = 'QPiB+6ErUaxztDxPn0oEJtwOE9uhNQjYISPC5jtyQpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}