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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9156e6a83b25e29706e117a97d6d7fd6f6cadb28bbb9f3469d2d61eda53d1037' 
  AND token = 'hyclVXN1OUgy2gz1XL+zhonzGTxT+fKh3CiUh2zsZDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}