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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb5e24427b84ed2f86e9f1f35216981aed128d8f995f7959d4ff737683b27b2' 
  AND token = 'yHMcNBuIlSDUR6UsfR3vIHmpS7cNo2mcGpiY4fcgmIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}