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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d80887eedd8d5b584fda3b06db0b91f3563db21cda4b5193455eadbacbf089' 
  AND token = 'rE+UtR4M1Qk5y3bSn8iIEhV5ce+IwHviGRYnA/pUkwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}