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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215a3e21a49b5c7783de1c05e43262ecc6bbc9fd753f0d136fe7448b06fc177f' 
  AND token = 'g0lpO+OWwfqEE3N8E/7xhHPV2FJF1TWvd6HrKqtO2nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}