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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a64deaae5d4430eeccc48485c52e7006da374b8434f508bc05c62d8efdbe5b2' 
  AND token = 'B/v72fd+A5ae3OuZjufjVanQrgXtyoptGO/eSrfZP+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}