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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efa5d719e2b4005fd4fa9e33b2a5e780ac746ab31f5281262279ae633795f8a' 
  AND token = '/PXkH6bb4GOt+qnxVSIfXnqYQ/Q6V4xuok8c3v5VlCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}