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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27367ecc3865de85c5e680c56ad0f35a6a16361a6eb6c19d55982ff4d88677ec' 
  AND token = 'QNEOHZCDVB8qh8FAAkidB5b5f+t9SZ+KriLMd4rvqHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}