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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd7eea35d68b4fd61ccaedd92f0ea34d7d06cc969d1f6dcec57896f75f695f4' 
  AND token = 'c8A/KB8Q9htYx0NJIDcfI3WBj79u218Xv6RU2GaGBPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}