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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6080dce6b4c417d3d30aa1e7de68f1122e64b4c9ce46d946bbe7bba58f0d0a7d' 
  AND token = '8CsG9h1i1mUOlOSpHGSL66QAD4wg8mL80Xg9Oo6Q8MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}