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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad263921c845301d807a6334595f5002f21aadc88193da8b5b8a98d45c0890c' 
  AND token = 'asBkukJnl+rbqk6Tu9Sty1vfHky2dVd+47UL2ZNFXEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}