SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f9f54284fb32d57870ec0886fe7b36cf274e35840d930cffc1c16461343587d' 
  AND token = '74Fn6Um6P2Fw6UYVsIjTd4BSCT7Ch2nDDZZ+s2VL3Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}