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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eddc7881305d9c47a50e61d12aee37c1d75a6bc923cf3758ca0ae3d008015251' 
  AND token = 'ET0oTnqgYG2vB3ZMP3tyo0MOXTz6e5ld+V35yxMhXWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}