SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e2dfcb9d878f107ab6517b50946e2c9090cc49c6ce4668fe42cdf93414a754' 
  AND token = 'HkcyLS1hDE75eIbs0/+zEEHLH1RjkYnBxeXfeS0rXFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}