SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a313e49792e8699abfef5c2b99ba638f3c2a4861cb03a1cd5c1151b429701a2' 
  AND token = 'mDy68m89UIQ+bMBsttWOuLATiikb+8h14rFM8s/1ZZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}