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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378b738753f4bc7697f7feeace025e8c68ae5a2867bf09da08f4abc25ec07895' 
  AND token = '9FkugRRz8f9Y70YdgMy2MyPanz0WF6w03FxPkVkmOW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}