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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb29cf8532f91a3ac7ce854f3c1e82c664e5a34d15dd2bcaf6014037374ed0ff' 
  AND token = 'tEiXwPHt5yELN4J3+mVe5r3uSCMyVqsBbMaHO5CdiEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}