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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721a1838afd8765dc3fcad0fe5d698b3f68838ca291921822136d3314042c7b8' 
  AND token = '9xdm22iD28i2Lh98XgnGhbkc7/tuv6OjYBDRnevCLV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}