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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f6c5ffb644e23545992c8a9dd8427cafc9c795eb01d62433d55187addd6a43' 
  AND token = 't8QI4TN2wxnNWhdu3Jk+RxrVCb/KxoowEDlnCkMiXwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}