SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4debfd4a7c7fe6c635c14300aaf38978890d950d346405c7ce304643b75ac6d0' 
  AND token = 'yTfIVAqnG3nKjLZtjoF1NCImgj7DDyM2s046DtVPurc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}