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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ad323861e8dcb60814ad948ad9d57f8500a1580044074d482d08892d2876f0' 
  AND token = 'zv4vS1Y4oRfS5KHmeNuVWR8mTiq0mcnLbrRF8yD2aVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}