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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5f9849e158d585c1798788bd36f9274a1bb5a4bdfbb38aed3a2fa8f48ba90d2' 
  AND token = '2/gQ1WDi/L2/VaRN70AtpmTaKqeV2rujYca47URtrs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}