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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c59eb63d00be9c6743e48f8cece7957d31cd6cfb1c0a8871f66acdac52f7cbe' 
  AND token = 'ewizK+Ip4tEizBCe+pWVDtnPT1ShPNV69f44PbHveLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}