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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c420331c3362684a9a28e3e693389c27639f9a54d59c5a0c6631dbd3f2aac338' 
  AND token = '2OdtfJaBmuWNQykL+d7HEAaOwC7IeExFyfNHBr4GBo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}