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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d53d85525c1db3d1438f959a0262181fac6ee6bfa8c837c731c511f1232480' 
  AND token = 'uzNVn0aBHxpdJlPh2rg1/zMAcVMgULsMlmu0KCndmxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}