SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae494ab01c9d0d91c05651d3976a7759b6a8e8284f42e5d9c8f7fb9c9fd4fded' 
  AND token = '+l6hKn2y7z29e3wADZjmIaBTJhS5Ci1nAkhWVddl0qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}