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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bcfb5dbd5e1742717096feea9ccd3b4f81a03312be26ad10334253d2d871c45' 
  AND token = 'EUHDz9cD2u/EmzSdlugTvcgSn5UMKAjxDlk5186c/P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}