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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757a55c255331120d664a79ec7f84744394c4da2bfce95f1ef2cb06427cc6cc1' 
  AND token = 'RnBEIthHZp4ezIV+eFpPxd4ilDyLYZa0fc2AMwBKQno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}