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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e6f9159b86f36ce72c0daf6105c8af90e4d4b1ada93a697c21042448d5c5a9' 
  AND token = 'IgH/6rDYxZ6TQV3nDZqsDg6gw7pSE37ZJ5Ou8JPmmHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}