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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e88db1c3ca52b04e9fae6607d4e49ca0505fe9c36cefe2d31b8754d2c146860' 
  AND token = 'JX5XVG3uprDTdCk81MVwiYh0RzULUz0ileEivLzhrf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}