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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7309421bdb12822c13b7982d1e5fe88c6aaa0af2ad98994cd97bb9c353fee48c' 
  AND token = 'gpvpiMg+sHeZ7BYMQru2ffMl8f5HTBzqRzOiy06CPPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}