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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f50eb314cef0ef31569046cfbdae2091813244dff4a03828f1c97207e627dd' 
  AND token = 'fSbUq7WRNDW4+WkgMn0oqggUHR1QIZ2iWSsYz8lVnl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}