SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1130271dcce3300bf61574a608d8d044859993bd000e2bf4687d9b03fa1486f' 
  AND token = '70OJ5M5GnQceRsQAM7JJFjmVX8uqCUn0VbQVeRRKhMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}