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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec483eba745a51c36ed78bce83e343f453192ac99bcf4829f5303b46f7700fcf' 
  AND token = '4H8GnUy1UrHRA11gY906bqbWzSblzSfnOu3nW+5kQP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}