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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d0e4cf094fb958a5ce0f56e6fc07e2d291ddb6a05486490f2791013763785b' 
  AND token = 'iDFcg0amNr2Klqq6D+XnxUjPV8O57s6X0HCVSWNk/Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}