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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f8a7d8625027859c3499a4aeb75897d58260ecba4fed54218a469ce30b5db7d' 
  AND token = 'Z4nzRCmvZxSG8y2AQe4S9d4xg+bAQYYkgBl/5J++cak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}