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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc12076e24ac4e41a2ce495087fa0e13463141be490e994108daf9ac0835421' 
  AND token = 'GdjyDiuzDZoSAQ5KaXSqE34OOU+/tHth8ooK6At1Bd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}