SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19199759376a577997b9bdd982013ce9f84ab40a15111436b09111a47326e55b' 
  AND token = 'MkJ4L8cY95d+EcgoAN4i5LnANZP+bKR+03guSmOANmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}