SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29235b6cc26f5d86aa6325433daa1c8c06f07c5012cd390f88779fe56dfbb652' 
  AND token = 'ZQpAEGTGJA8c7ACXOr/nnF6pF+8VWltOoVuNfEZyZG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}