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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7a6b5e18a3f46f45395e551ab627d0f4c2d2b5311e24309a16febe052188dbe' 
  AND token = 'k1ViE1t7uepgxAEYhB/iyI2I7EpGXN+HlzNJIMVCVsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}