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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f8d48d8aa02378a3283fc2a0ed23c8f0836914fda8d023556136a1db403819' 
  AND token = 'o8G0uC1aO2IFg/j1+n0IebvB5Due9Iga4SPYzchiEgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}