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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63a00fde541059269fe1ed233ccfeb3b5264fcdf844727908d1e5a31a66c6202' 
  AND token = 'MDCxP9h/9CfTTSeQ5VrIVNa3tKrK27DCcKMuv/Da4W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}