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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb465d54a106e9a6566031599e7cd2b03bacbfa1c672040ae354627683c9100' 
  AND token = 'rd1oAYF8jf5qgoYEfRfiiTb4clR/isNKY/8c+8slqPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}