SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258f373f1fe4ee4f28e57c2e2f7722289a3e5723d9da04ba81ce8871d38ea81a' 
  AND token = '5YNCBJ1aY+4hOxALwz/KHokUE+d1JekFKVXFbsCsAIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}