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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f0e258d6e4db1a21b6383c82fe1151624635e97ee844db79fb34dc20a6a5a7' 
  AND token = 'VD3e+s3ojbyZk3pna1WJVpW2HhyZW9BIC3cqGZZXVMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}