SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e421744c889533d257257ed7f0b01565d6f308e16e77b187799be13fc163ac5' 
  AND token = 'nQPs4o7WQIKsvoD/85vN9bgnSRkP9Ca3noY7v+oy0l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}