SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a135f9bc470b1e411dbf1d590816d3f5a95b24529194947b676b920b35a0b4d3' 
  AND token = 'qGO4dKgq+H7dRCUnLqT16+bbNnYBE727xcCMYCwar6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}